刘 颖

发布者:伟德国际官方入口发布时间:2021-11-03浏览次数:3357

刘颖,教授

基本信息

办公电话:021-51322210

电子邮箱:debbyly@shutcm.edu.cn

通讯地址:上海市浦东新区蔡伦路1200

招生专业

研究方向:中药新型给药系统

院系名称:伟德国际官方入口

学位类型:学术学位

专业名称:中药学/100800

教育经历

1997-092002-07, 沈阳药科大学, 药学(日语),学士

2002-092005-07, 沈阳药科大学,药剂学, 硕士

2007-092010-07, 上海中医药大学,中药学,博士

任职经历

2005-082007-12,上海中医药大学,助教

2006-092007-02,英国伦敦都市大学,访问学者

2008-012011-12,上海中医药大学,讲师

2012-012021-12,上海中医药大学,副教授

2017-092018-08, 上海交通大学,访问学者

2022-01至今,上海中医药大学,教授

获奖及荣誉

科研方面主要从事中药新型口服给药系统及抗肿瘤纳米递药系统的研究。主持国家自然科学基金项目、上海市科委自然科学基金项目、上海市教委科研项目等多项课题研究。发表学术论文50余篇,其中在专业领域期刊如JCRJ NanobiotechnolCEJ等发表一作、通讯作者文章10余篇。获授权国家发明专利4项。主译译著1部。曾获上海市科技进步奖和中华医学科技奖。兼任世中联中药药剂专委会理事、世中联中药新型给药系统专业委员会理事、中华中医药学会中药制剂分会委员、上海市药学会药剂专委会基础药剂学组组员。

教学方面主要从事与中药药剂学、药剂学相关的教学工作。副主编或参编国家规划教材多部。主持上海市课程建设项目1项,承担校级教学研究项目4项,发表教学论文多篇。2021年入选上海中医药大学金牌教师。

承担科研项目情况

  1. 国家自然科学基金面上项目,药对联合口服生理屏障级联响应纳米粒共调控M1/M2巨噬细胞极化和糖代谢失衡抗乳腺癌转移(82173988),主持

主要代表性成果

  1. Gu XY1, Zhang RG1, Sun YW, Ai XY, Wang Y, Lyu YQ, Wang XY, Wu YH, Wang Z, Feng NP*, Liu Y *. Oral membrane-biomimetic nanoparticles for enhanced endocytosis and regulation of tumor-associated macrophage. Journal of Nanobiotechnology, 2023, 21:206. ( IF 10.2)

  2. Liu Y *,1, Shen JY1, Shi JP, Gu XY, Chen HZ, Wang XY, Wang LX, Wang P, Hou XF, He YZ, Zhu CY, Wang, Guo T, Guo SR *, Feng NP*. Functional polymeric core–shell hybrid nanoparticles overcome intestinal barriers and inhibit breast cancer metastasis. Chemical Engineering Journal, 2022, 427, 131742. (IF 15.1)

  3. Gu XY1, Gao YZ1, Wang P1, Wang LX, Peng HB, He YZ, Liu Y*, Feng NP*. Nano-delivery systems focused on tumor microenvironment regulation and biomimetic strategies for treatment of breast cancer metastasis. Journal of controlled release, 2021,333:374-390. ( IF 11.467)

  4. Liu Y1, Xie XM1, Hou XF, Shen JY, Shi JP, Chen HZ, He YZ, Wang Z, Feng NP*. Functional oral nanoparticles for delivering silibinin and cryptotanshinone against breast cancer lung metastasis. Journal of Nanobiotechnology, 2020, 18(1):83. (IF 10.435)

  5. Liu Y1, Xie XM1, Chen HZ, Hou XF, He YZ, Shen JY, Shi JP, Feng NP*. Advances in next-generation lipid-polymer hybrid nanocarriers with emphasis on polymer-modified functional liposomes and cell-based-biomimetic nanocarriers for active ingredients and fractions from Chinese medicine delivery. Nanomedicine: Nanotechnology, Biology and Medicine, 2020, 29:102237. (IF= 6.458)

  6. Liu Y1, Jiang ZF1, Hou XF, Xie XM, Shen JY, Shi JP, He YZ, Wang Z, Feng NP*. Functional lipid polymeric nanoparticles for oral drug delivery: Rapid mucus penetration and improved cell entry and cellular transport. Nanomedicine: Nanotechnology, Biology and Medicine. 2019, 21:102075. (IF= 5.182)

  7. Liu Y1, Huang PW1, Hou XF, Yan F, Jiang ZF, Shi JP, Xie XM, Shen JY, Fan QY, Wang Z, Feng NP*. Hybrid curcumin–phospholipid complex-near infrared dye oral drug delivery system to inhibit lung metastasis of breast cancer. International Journal of Nanomedicine, 2019,14:3311-3330. (IF=5.115)

  8. Liang J1, Liu Y 1, Liu JG, Li Z, Fan QY, Jiang ZF, Yan F , Wang Z, Huang PW, Feng NP*. Chitosan-functionalized lipid-polymer hybrid nanoparticles for oral delivery of silymarin and enhanced lipid-lowering effect in NAFLD. Journal of Nanobiotechnology, 2018,16(1):64. (IF=5.345)

  9. Wang Y1, Wang FH1, Liu Y1, Xu SH, Shen YY, Feng NP*, Guo SR*. Glutathione detonated and pH responsive nano-clusters of Au nanorods with a high dose of DOX for treatment of multidrug resistant cancer. Acta Biomaterialia, 2018,75:334–345. ( IF=6.97)

  10. 《基于脂质的纳米载体在药物递送和诊断中的应用》,刘颖. 科学出版社,20199, ISBN 9787-030613486.